DC MACS/WIHS Combined Cohort Study & The Study of Treatment And Reproductive Outcomes

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Learn more about the DC MWCCS & STAR Studies!


“It’s been a long journey for me. I was really devastated when I got the virus. But when I started the study I could ...

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As of January 1, 2019, the MACS and WIHS cohorts combined to form the MACS/WIHS Combined Cohort Study (MWCCS).

The Multicenter AIDS Cohort Study (MACS) / Women’s Interagency HIV Study (WIHS) Combined Cohort Study (MACS/WIHS-CSS) is a collaborative research effort that aims to understand and reduce the impact of chronic health conditions—including heart, lung, blood, and sleep (HLBS) disorders—that affect people living with HIV.

For decades, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health (NIH), has supported the separate MACS and WIHS cohort studies. MACS was a study of gay and bisexual men, while WIHS was a study of women who had other risk factors for HIV.

In 2019, the NHLBI became the primary steward of the new MACS/WIHS-CSS. For this effort, the NHLBI is working in close collaboration with the NIH Office of AIDS Research (OAR) as well as several co-funding institutes across the NIH.                                   

This photo displays other MWCCS and STAR sites across the nation.